What is the Entourage Effect? The science behind the research

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The cannabis plant contains a multitude of compounds, called cannabinoids. While the best known cannabinoid is THC, there are actually over 100 different cannabinoids present in the cannabis plant. Each of these compounds plays an important role, and each has its own benefits.

To get the most out of your cannabis experience, it helps to understand the science behind what makes it so unique. There is a lot of research being conducted on this topic, but here are some key points to know about the entourage effect and how it can help you improve your high.

What is the entourage effect? This is one of the many ways researchers are exploring how all of these cannabinoids work together in tandem to create such a beneficial experience for users. Let’s go further…

What is the endocannabinoid system?

The endocannabinoid system (ECS) is a set of receptors and corresponding molecules involved in many physiological processes. The ECS is responsible for maintaining homeostasis in the face of stress, injury or environmental change. For example, when we exercise, our bodies produce more free radicals, which can damage the cells in our bodies. The ECS system is activated in response to increased oxygen radicals, and it uses cannabinoids to reduce the damage caused by these radicals. The ECS plays an important role in the regulation of mood, appetite, sleep, immune function and many other important processes. This system is sensitive to the compounds found in cannabis, which is why cannabis use has such powerful effects on the body.

How does the entourage effect work?

Theentourage effect describes the belief that all the compounds in cannabis work together to create a more beneficial effect. While not all researchers believe this is actually the case, many studies show that THC and CBD work best when combined with other cannabinoids. Some cannabinoids are anti-inflammatory, antioxidant and can reduce pain. THC and CBD are the two best studied cannabinoids, and they create a strong euphoric effect when consumed together. However, the addition of other cannabinoids weakens the euphoria created by THC while increasing the therapeutic effects of CBD. This suggests that the benefit of cannabis use comes from the interaction between cannabinoids, not from the euphoria created by one or two specific cannabinoids.

infographic explaining the entourage effect of cannabidiol CBD

THC and CBD are essential

Several different cannabinoids contribute to the entourage effect, but THC and CBD are the main drivers. Other cannabinoids also have a strong impact on JIT, but research on THC and CBD is the most conclusive. The two most important cannabinoids are THC and CBD. Both cannabinoids offer medicinal benefits, but only when taken together. Researchers believe that the reason THC and CBD work so well together is because they have opposite properties. THC is a weak anti-inflammatory compound and CBD is a strong anti-inflammatory compound. When these two substances are consumed together, they create a much stronger anti-inflammatory effect than if they were consumed separately.

Other cannabinoids are also important

While THC and CBD are the most important cannabinoids, there are a number of other cannabinoids that influence the overall experience. The third most studied cannabinoid is CBG, but this cannabinoid has not been studied as much as THC and CBD. However, researchers studying CBG have found that it is an anti-inflammatory and antioxidant compound. This means that CBG can reduce pain, inflammation and oxidative damage in the body. Other cannabinoids also have medicinal properties, but they have been the subject of much less research.

Final thoughts

The entourage effect is a term used to describe the theory that all the compounds in cannabis work together to create a more beneficial effect. While the entourage effect is not an exact science, a lot of research shows that THC and CBD work best when combined with other cannabinoids. The two most important cannabinoids are THC and CBD. Both cannabinoids provide medicinal benefits, but only when consumed together. The addition of other cannabinoids weakens the high created by THC while increasing the therapeutic effects of CBD. Other cannabinoids also have medical benefits, but they have been much less researched. As more research is conducted on the cannabis plant, we will better understand how all these cannabinoids work together to create such a beneficial experience for users.

Also read: Growing Hemp indoors, outdoors and in greenhouses: what is the difference?

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